https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Late gestation immune activation increases IBA1-positive immunoreactivity levels in the corpus callosum of adult rat offspring https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33669 Iba1, Gfap, IL1-β and TNF-α mRNA levels in the cingulate cortex (CC) in adult offspring exposed to maternal immune activation. Prenatal exposure to immune activation had a significant main effect on microglial IBA1-positive immunoreactive material (IBA1+IRM) in the corpus callosum; post-hoc analyses identified a significant increase in GD19 offspring, but not GD10. No change in was observed in the CC. In contrast, maternal immune activation had a significant main effect on GFAP+IRM in the CC at GD19 (not GD10); post-hoc analyses only identified a strong trend towards increased GFAP+IRM in the GD19 offspring, with no white matter changes. This suggests late gestation maternal immune activation causes subtle alterations to microglia and astrocytes in the adult offspring.]]> Tue 04 Jun 2019 13:36:19 AEST ]]> Reduced cortical somatostatin gene expression in a rat model of maternal immune activation https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:46136 Thu 29 Jun 2023 12:51:13 AEST ]]> Neonatal immune challenge alters reproductive development in the female rat https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:21584 Sat 24 Mar 2018 08:00:44 AEDT ]]>